What is Non-Alcoholic Fatty Liver Disease (NAFLD)?
Non-alcoholic fatty liver disease (NAFLD) is a liver disease affecting people who drink little to no alcohol. As the name implies, the main characteristics of NAFLD is too much fat stored in liver cells. NAFLD is increasingly common around the world, especially in Western nations. In the United States, it is the most common form of chronic liver disease, affecting about one-quarter of the population. NAFLD is the most common liver disease in Canada affecting about 20% of Canadians. It tends to develop in people who are overweight or obese, particularly if they have lot of fat around the middle of their body (waist). It can also develop in a person whose body weight is in the healthy weight range, but who typically eats a lot of sugary and fatty foods and who has extra fat around the waist. The most common cause of fatty liver disease in Canada is obesity. In 2018, almost 30% of Canadians 18 and older (roughly 7.3 million adults) reported height and weight that classified them as either overweight or obese. NAFLD has shown to be strongly associated with metabolic syndrome- a health disorder characterized by a group of risk factors (large waist circumference, high blood pressure, high blood sugar levels, high cholesterol, and abnormal amounts of lipids in the blood) that greatly increase the risk of many chronic illnesses. Some individuals with NAFLD can develop nonalcoholic steatohepatitis (NASH), an aggressive form of fatty liver disease, which is marked by liver inflammation and may progress to advanced scarring (cirrhosis) and liver failure. This damage is similar to the damage caused by heavy alcohol use. The main complication of NAFLD and NASH is cirrhosis, which is late-stage scarring in the liver. Cirrhosis occurs in response to liver injury, such as the inflammation in NASH. As the liver tries to halt inflammation, it produces areas of scarring (fibrosis). With continued inflammation, fibrosis spreads to take up more and more liver tissue. A wide range of diseases and conditions can increase your risk of NAFLD, including:
High levels of triglycerides in the blood
Obesity, particularly when fat is concentrated in the abdomen
Polycystic ovary syndrome
Type 2 diabetes
Underactive thyroid (hypothyroidism)
Underactive pituitary gland (hypopituitarism)
These combined health problems appear to promote the deposit of fat in the liver. For some people, this excess fat acts as a toxin to liver cells, causing liver inflammation and NASH, which may lead to a buildup of scar tissue in the liver.
To reduce your risk of NAFLD:
Choose a healthy diet. Choose a healthy plant-based diet that’s rich in fruits, vegetables, whole grains and healthy fats.
Maintain a healthy weight. If you are overweight or obese, reduce the number of calories you eat each day and get more exercise. If you have a healthy weight, work to maintain it by choosing a healthy diet and exercising.
Exercise. Exercise most days of the week. Get an OK from your doctor first if you haven’t been exercising regularly.
For individuals with NASH who are not overweight and not diabetic, a diet with lower fat foods without a lot of added sugars is often recommended.
Those with diabetes and high lipids in their blood have to improve their sugar control and lower lipids levels. Usually, a lower fat, lower calorie diet with avoidance of sugary foods is recommended along with insulin or medications to lower blood sugar in people with diabetes. If you have diabetes, please see your healthcare provider who can advise you how to manage your diabetes.
People with fatty liver disease should see their primary healthcare providers on a regular basis and seek out the advice of a dietitian regarding their diet.
By adopting a healthy lifestyle, you may prevent obesity – the number one reason for fatty liver disease. Please remember that a healthy diet and exercise are important components of any weight-loss regimen. Introduce exercise into your routine, at least four times a week. You can enjoy walking, swimming, gardening, stretching.
Anxiety and menopause
Most women make the transition into menopause without experiencing a major mood disorder. Estimates of the prevalence of mood disorders are inconsistent and vary greatly but range from 12% to as many as 50% of women who will experience mood symptoms or disorders during this transitional time in their lives. Although many studies have assessed risk of depression during the perimenopausal transition, few have systematically investigated the relationship between menopause and anxiety, although prevalence of anxiety in midlife women is substantial. Cognitive changes that frequently occur during perimenopause are not typically associated with neurodegeneration, they may lead to undue worry about early-onset dementia. Since there are parallels and overlapping symptoms between hot flashes and panic attacks, women prone to panic attacks cannot always differentiate between the two. As many as 51% of women aged 40 to 55 years report occasional tension, nervousness or irritability and 25% report frequent irritability or nervousness.
Hormone changes, life stresses, sleep problems, worries about body image, infertility, and aging are all factors linked to menopause that can contribute to mood swings, stress, anxiety, and a decreased sense of well-being in women. Few scientific studies support the idea that menopause contributes to true clinical depression, severe anxiety, or change behavior. Studies report that 23%of women experience symptoms of anxiety during perimenopause and that these symptoms of anxiety are not necessarily linked to depression. Additionally, symptoms of anxiety—tension, nervousness, panic, and worry—are reported more frequently during perimenopause than before it, regardless of whether symptoms of depression are present or not. At the same time, hormone fluctuations, life stresses, sleep troubled by night sweats, and concerns about body image, infertility, and aging can all cause emotional distress that may lead to mood swings or, in more severe cases, depression. Many women report symptoms of depressed mood, stress, anxiety, and a decreased sense of well-being around the time of menopause. The hormonal changes that happen during menopause can also drive feelings of anxiety. Changes in levels of hormones called estrogen and progesterone in particular, can have an impact. The variability in estrogen levels rather than the diminished levels, per se, may be associated with mood symptoms. It is known that fluctuating levels of estradiol increase the risk of vasomotor symptoms, which positively correlate with anxiety during perimenopause. It is also possible that impaired gamma-aminobutyric acid (GABA) receptor modulation of the hypothalamus-pituitary-adrenal axis during the menopausal transition may prolong the stress response, thereby increasing anxiety. Many women experience panic attacks during the menopause. Because people that have had panic attacks before are more likely to experience panic attacks during perimenopause, doctors think that panic attacks are a reaction to rather than a symptom of menopause.When someone has a panic attack, they experience intense feelings of anxiety or “doom.” These feelings may be accompanied by physical symptoms, such as:heart palpitations, shortness of breath, dizziness, weakness, sweating, nausea, tingling sensations.Many people experiencing a panic attack for the first time worry that they are having a heart attack or a nervous breakdown. Panic attacks can be among the most terrifying experiences of a person’s life.If someone has panic attacks, they should speak to their doctor.
Depression, mood, and sex. The relationship between sexuality and depression or mood state is often complicated. Depression can be both a cause and a result of a sexual problem. For instance, a woman’s loss of desire may contribute to her depression, yet she also may see her desire decline as an effect of depression. Additionally, mood affects emotion, which affects relationship issues, which in turn have implications for sex.
Although low desire is the most frequent sexual side effect of depression or anxiety, other aspects of sexuality can also be affected. In women, orgasm may be more difficult to achieve when depression is present.
Women with moderate to severe depression or anxiety will often be prescribed the popular antidepressant drugs known as SSRIs (selective serotonin reuptake inhibitors). Although the SSRIs are often effective in improving depression or anxiety, for many women (and men) they carry sexual side effects that include diminished sexual desire, trouble achieving and maintaining arousal, and difficulty achieving orgasm.Doctors believe that following a healthful lifestyle both helps with menopause symptoms and reduces panic attacks.Regular, gentle exercise can significantly reduce anxiety. Women who are going through perimenopause should pick their favorite form of exercise and try to make it part of a daily routine. Whether it is walking, running, swimming, or yoga, regular exercise can help to burn off nervous energy and improve symptoms of anxiety.Getting good-quality sleep is important for reducing anxiety. However, women going through menopause often sleep poorly due to night sweats caused by hormone surges. Importantly, women should make sure that they take time out for themselves. Certain activities, such as gardening, reading, meditating, practicing mindfulness, or yoga, are all good ways to focus on oneself and create feelings of well-being and relaxation.
InSea2® – A unique dual action glucose optimizer.
Diabetes mellitus is a heterogeneous metabolic disorder characterized by the presence of hyperglycemia due to impairment of insulin secretion, defective insulin action or both. The chronic hyperglycemia of diabetes is associated with relatively specific long-term microvascular complications affecting the eyes, kidneys and nerves, as well as an increased risk for cardiovascular disease. The majority of cases of diabetes can be classified into 2 categories: type 1 diabetes and type 2 diabetes, although some cases are difficult to classify. Type 2 diabetes is a disease in which your body cannot make enough insulin, or your body does not properly use the insulin it makes. Insulin is a hormone that helps your body to control the level of sugar in your blood. As a result, glucose (sugar) builds up in your blood instead of being used for energy. If left unmanaged, the excess sugar in your blood can eventually cause problems and lead to serious health complications. Type 2 diabetes can sometimes be managed with healthy eating and regular exercise alone, but may also require medications or insulin. Maintenance of blood glucose is one of the cornerstones of our health.
InSea2® is a unique and natural ingredient that helps support healthy blood glucose levels and maintain optimal insulin functions by slowing down starch and sugar absorption. Most carbohydrates come in a form that cannot be assimilated straight away. This is why the human digestive system uses enzymes to convert these carbs into glucose, the form of carbs that enters the bloodstream and nourishes body cells. This digestive process needs to be repeated meal after meal to ensure optimal body functions. InSea2® is a natural dual action α-amylase and α-glucosidase inhibitor, two key enzymes involved in the digestion and assimilation of starch and sugar. InSea2® thus reduces the glycemic stress that follows a meal as well as the associated insulin peak, and helps sustain healthy insulin sensitivity. By using InSea2® before each meal, carbs are converted into glucose at a much slower pace, reducing the glycemic stress and generating immediate and long-term health benefits. And moreover, unlike other ingredients that takes weeks or months to have an effect you can feel, InSea2® works immediately upon first use!
Clinical studies show that InSea2® can reduce post-meal blood glucose levels by 48,3%, insulin levels by 12,1% and improve insulin sensitivity by 7,9% immediately upon the first use of the product. In addition to its immediate effects, InSea2® also provides long term benefits on glycemic health when taken on a daily basis. In a recent randomized, double-blind, placebo-controlled clinical trial performed over a six-month period, InSea2® showed tremendous potential to preserve long term optimal glycemic health in challenged individuals, with most subjects improving or even reverting to an optimal glycemic state. In the current context of high consumption of toxic added sugars, reducing unwanted large fluctuations in blood glucose and insulin after a meal is a strong ally in maintaining long-term glycemic health. Even in absence of diabetes, large blood glucose fluctuations are generated every day by our diet, rich in added sugars. “Fluctuations” means that shortly after a high-carb meal, blood glucose will reach levels so high that glucose itself has toxic impacts on our body through glycation or by triggering oxidative stress. Glycation and oxidative stress create direct damages to DNA, proteins, and lipids. “Fluctuations” also means that high blood glucose levels generate a large insulin release that will in turn induce a steep decline in blood glucose a few hours later, reaching hypoglycemic levels. These fluctuations are responsible for the extensive consequences associated with poor blood glucose control. The exceptional quality of InSea2 starts with wild brown seaweeds harvested in the clear waters of the North Atlantic Ocean than followed by a green an sustainable extraction process that concentrates polyphenols in their native conformation, preserving their enzymes- blocking capacity to help maintain healthy blood glucose levels and optimize the bodys energy management after a meal.
InSea2 has also a strong antioxidant potency to protect agains free redical damages and accelerated aging.